Angiogenesis inhibitors have shown promise in hindering blood supply and holding tumors in check. But it now seems that such inhibitors, by depriving tumors of oxygen, could have an unintended effect: promotion of metastasis.
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Steeg, P. Angiogenesis inhibitors: motivators of metastasis?. Nat Med 9, 822–823 (2003). https://doi.org/10.1038/nm0703-822
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DOI: https://doi.org/10.1038/nm0703-822
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