Efp: A ring of independence?

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Breast cancer patients who respond to tamoxifen and other estrogen-antagonizing drugs can succumb to disease when cancer growth becomes independent of the hormone. One protein, Efp, that might have a role in estrogen independence has now been linked to proteolytic events in the cell cycle.

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Figure 1: The estrogen-inducible RING finger protein Efp stimulates proliferation of breast cancer cells.

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