Basophils have recently been identified as antigen-presenting cells that are required for optimal antibody responses. New findings now show that activation of these cells can amplify autoimmune responses in systemic lupus erythematosus (SLE) (pages 701–707).
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References
Charles, N. et al. Nat. Med. 16, 701–707 (2010).
Denzel, A. et al. Nat. Immunol. 9, 733–742 (2008).
Chen, K. et al. Nat. Immunol. 10, 889–898 (2009).
Sokol, C.L. et al. Nat. Immunol. 10, 713–720 (2009).
Yoshimoto, T. et al. Nat. Immunol. 10, 706–712 (2009).
Komiya, A. et al. Int. Arch. Allergy Immunol. 140 Suppl 1, 23–27 (2006).
Silver, K.L. et al. Eur. J. Immunol. 37, 2734–2743 (2007).
Tsantikos, E. et al. J. Immunol. 184, 1348–1360 (2010).
Singh, R.R. et al. J. Immunol. 170, 4818–4825 (2003).
Hayashi, T. et al. Nephrol. Dial. Transplant. 22, 3131–3138 (2007).
Tucci, M., Lombardi, L., Richards, H.B., Dammacco, F. & Silvestris, F. Clin. Exp. Immunol. 154, 247–254 (2008).
Hsu, H.C. et al. Nat. Immunol. 9, 166–175 (2008).
Simpson, N. et al. Arthritis Rheum. 62, 234–244 (2010).
O'Shea, J.J. & Paul, W.E. Science 327, 1098–1102 (2010).
Atta, A.M., Santiago, M.B., Guerra, F.G., Pereira, M.M. & Sousa Atta, M.L. Int. Arch. Allergy Immunol. 152, 401–406 (2010).
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Davidson, A., Diamond, B. Activated basophils give lupus a booster shot. Nat Med 16, 635–636 (2010). https://doi.org/10.1038/nm0610-635
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DOI: https://doi.org/10.1038/nm0610-635
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