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Bone loss goes beyond estrogen

The central position of estrogen in the physiological and pharmacological control of bone resorption is now challenged by evidence from mouse genetics of estrogen-independent control by pituitary FSH.

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Figure 1: The potential effects of FSH on the skeleton in vivo, either directly upon bone or indirectly.

Katie Ris

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Martin, T., Gaddy, D. Bone loss goes beyond estrogen. Nat Med 12, 612–613 (2006). https://doi.org/10.1038/nm0606-612

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