Marijuana receptors are present in fibrogenic cells of the liver, and their expression is induced in cirrhosis. Blockade of the CB1 subtype is now shown to inhibit fibrogenesis, offering a new approach for the treatment of cirrhosis (pages 671 – 676).
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References
Friedman, S.L. Nat. Clin. Pract. Gastr. Hepatol. 1, 98–105 (2004).
Teixeira-Clerc, F. et al. Nat. Med. 12, 671–676 (2006).
Howlett, A.C. et al. Neuropharmacol. 47 (Suppl. 1), 345–358 (2004).
Julien, B. et al. Gastroenterology 128, 742–755 (2005).
Hézode, C. et al. Hepatology 42, 63–71 (2005).
Siegmund, S.V. et al. Hepatology 41, 983–995 (2005).
Bátkai, S. et al. Nat. Med. 7, 827–832 (2001).
Ros, J. et al. Gastroenterology 122, 85–93 (2002).
Gaskari, S.A. et al. Br. J. Pharmacol. 146, 315–323 (2005).
Osei-Hyiaman, D. et al. J. Clin. Invest. 115, 1298–1305 (2005).
Farrell, G.C. & Larter, C.Z. Hepatology 43, S99–S112 (2006).
Després, J.P. et al. N. Engl. J. Med. 353, 2121–2134 (2005).
Ikejima, K. et al. Gastroenterology 122, 1399–1410 (2002).
Kamada, Y. et al. Gastroenterology 125, 1796–1807 (2003).
Friedman, S.L. & Bansal, M. B Hepatology 43, S82–S88 (2006).
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Kunos, G., Osei-Hyiaman, D., Bátkai, S. et al. Cannabinoids hurt, heal in cirrhosis. Nat Med 12, 608–609 (2006). https://doi.org/10.1038/nm0606-608
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DOI: https://doi.org/10.1038/nm0606-608
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