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Shrinking prions: new folds to old questions

Abstract

Transgenic mice and recombinant proteins offer surprising insights into the details of prion replication.

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Figure 1: Top, Cellular prion protein (PrPC).
Figure 2: Possible interpretation of the findings reported by Supattapone and colleagues.

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Aguzzi, A., Brandner, S. Shrinking prions: new folds to old questions. Nat Med 5, 486–487 (1999). https://doi.org/10.1038/8366

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