Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Beyond building proteins: tRNA synthetases outside of translation

This is a preview of subscription content, access via your institution

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. Kleeman, T.A., Wei, D., Simpson, K.L. & First, E.A. J. Biol. Chem. 272, 14420–14425 (1997).

    Article  CAS  Google Scholar 

  2. Wakasugi, K. & Schimmel, P. Science 284, 147–151 (1999).

    Article  CAS  Google Scholar 

  3. Fox, P.L. RNA 21, 615–618 (2015).

    Article  CAS  Google Scholar 

  4. Yao, P. & Fox, P.L. EMBO Mol. Med. 5, 332–343 (2013).

    Article  CAS  Google Scholar 

  5. Jordanova, A. et al. Nat. Genet. 38, 197–202 (2006).

    Article  CAS  Google Scholar 

  6. Froelich, C.A. & First, E.A. Biochemistry 50, 7132–7145 (2011).

    Article  CAS  Google Scholar 

  7. He, W. et al. Nature 526, 710–714 (2015).

    Article  CAS  Google Scholar 

  8. Kim, D., Kwon, N.H. & Kim, S. Top Curr. Chem. 344, 207–246 (2014).

    Article  CAS  Google Scholar 

  9. Park, M.C. et al. Proc. Natl. Acad. Sci. USA 109, E640–E647 (2012).

    Article  CAS  Google Scholar 

  10. Williams, T.F., Mirando, A.C., Wilkinson, B., Francklyn C.S. & Lounsbury K.M. Sci. Rep. 3, 1317 (2013).

    Article  Google Scholar 

  11. Wellman, T.L. et al. BMC Cancer 14, 620 (2014).

    Article  Google Scholar 

  12. Fang, P. et al. Nat. Commun. 6, 6402 (2015).

    Article  CAS  Google Scholar 

  13. Mirando, A.C. et al. Sci. Rep. 5, 13160 (2015).

    Article  CAS  Google Scholar 

  14. Zhou, J.J. et al. J. Biol. Chem. 289, 19269–19275 (2014).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Becker, R. Beyond building proteins: tRNA synthetases outside of translation. Nat Med 22, 452–453 (2016).

Download citation

  • Published:

  • Issue Date:

  • DOI:


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing