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Getting to the bare bones of fertility

Nature Medicine volume 17, pages 550–551 (2011)Cite this article

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Sundeep Khosla

The past several decades have witnessed a major evolution in our view of bone. Initially considered a relatively uninteresting scaffold for the rest of the body, bone is now recognized as a fascinating organ that is regulated by several local and systemic factors. More recently, several groups, particularly the laboratory of Gerard Karsenty1,2, have added another twist to our understanding of the role of bone, showing how the skeleton seems to be a crucial endocrine organ and how osteocalcin, which is produced by bone-forming osteoblast cells, is perhaps its most prominent hormone.

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Getting to the bare bones of fertility. Nat Med 17, 550–551 (2011). https://doi.org/10.1038/nm0511-550

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