Calling all antigens

Many parasites vary their surface molecules to avoid the host's immune response, thereby perpetuating long-term infections. Disrupting this process in the intestinal parasite Giardia lamblia now provides a useful tool for vaccination (pages 551–557).

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Figure 1: Successful vaccination with G. lamblia parasites that simultaneously express multiple surface antigens.

Kimberly Caesar

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Correspondence to Kirk Deitsch.

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Deitsch, K. Calling all antigens. Nat Med 16, 522–523 (2010). https://doi.org/10.1038/nm0510-522

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