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Dust mites' dirty dealings with dendritic cells

Allergens stimulate lymphocytes to become factories for secreted proteins that cause organ dysfunction in allergic diseases. Allergens are now shown to target dendritic cells, the cells responsible for processing and presenting antigens to T cells (pages 565–573).

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Figure 1: Direct effects of allergens and allergy-inducing adjuvants on dendritic cells.

Kim Caesar

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Sheppard, D. Dust mites' dirty dealings with dendritic cells. Nat Med 14, 487–488 (2008). https://doi.org/10.1038/nm0508-487

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