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β-adrenergic signaling in heart failure—adapt or die

About 25% of the African-American population carries a gene variant that seems to protect against heart failure. The findings may have implications for the use of β-blockers (pages 510–517).

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Figure 1: Vicious cycle in heart failure.

Kim Caesar


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Eschenhagen, T. β-adrenergic signaling in heart failure—adapt or die. Nat Med 14, 485–487 (2008).

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