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The bridge between dendritic cells and asthma

A single molecule, osteopontin, seems to both amplify and quell the immune response in asthma—depending on the stage of the asthmatic reaction. The findings hint that, if given at the right stage, osteopontin might have value as a therapy (pages 570–578).

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Figure 1: Regulation of dendritic cell migration in airway hypersensitivity (AHR) by Opn-s.

Kim Caesar


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Shinohara, M., Cantor, H. The bridge between dendritic cells and asthma. Nat Med 13, 536–538 (2007).

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