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Channeling pain

Nature Medicine volume 12, pages 506–507 (2006)Cite this article

In vitro experiments have suggested that the TRPA1 ion channel senses various noxious stimuli. Many of these findings are now borne out in mice, in line with the notion that TRPA1 inhbitors might be useful in treating pain.

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Figure 1: TRPA1 is a polymodal nociceptor of various noxious stimuli.

Katie Ris

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Authors and Affiliations

  1. The Scripps Research Institute, La Jolla, 92037, California

    Ardem Patapoutian & Lindsey Macpherson

  2. Genomics Institute of the Novartis Research Foundation, San Diego, 92121, California, USA

    Ardem Patapoutian & Lindsey Macpherson

Authors
  1. Ardem Patapoutian
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  2. Lindsey Macpherson
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Patapoutian, A., Macpherson, L. Channeling pain. Nat Med 12, 506–507 (2006). https://doi.org/10.1038/nm0506-506

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