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Do-all receptor takes on coagulation, inflammation

Nature Medicine volume 11, pages 475–477 (2005)Cite this article

How many critical functions can be jammed into one receptor? New work on thrombomodulin explores the limits. This already overtaxed protein binds HMGB1, a molecule that contributes to sepsis and other inflammatory conditions.

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Figure 1: Multitasking molecule.

Katherine Ris

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  1. Howard Hughes Medical Institute at the Oklahoma Medical Research Foundation, Oklahoma City, 73104, Oklahoma, USA

    Charles Esmon

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  1. Charles Esmon
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Esmon, C. Do-all receptor takes on coagulation, inflammation. Nat Med 11, 475–477 (2005). https://doi.org/10.1038/nm0505-475

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