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Infectious triggers for inflammatory neurological diseases

Do autoimmune diseases develop 'spontaneously' or are they induced by environmental triggers, such as infectious agents? This is a central—and challenging—question in the autoimmunity field. A new study in this issue provides strong evidence for a virus-induced autoimmune process in a human neurological disease. (pages 509–513)

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Figure 1: Infection by HTLV-1 leads to a persistent infection of T cells and the production of antibodies to viral antigens.

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Wucherpfennig, K. Infectious triggers for inflammatory neurological diseases. Nat Med 8, 455–457 (2002). https://doi.org/10.1038/nm0502-455

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