Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Dropping acid to help cystic fibrosis

Vesicular accumulation of the membrane component ceramide may underlie key aspects of lung pathology in cystic fibrosis (pages 382–391).

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Enhancing inflammation and infection in the cystic fibrosis–affected airway.

Kim Caesar

References

  1. Teichgräber, V. et al. Nat. Med. 14, 382–391 (2008).

    Article  Google Scholar 

  2. Grassme, H. et al. Nat. Med. 9, 322–330 (2003).

    Article  CAS  Google Scholar 

  3. Campodonico, V.L., Gadjeva, M., Paradis-Bleau, C., Uluer, A. & Pier, G.B. Trends Mol. Med. 14, 120–133 (2008).

    Article  CAS  Google Scholar 

  4. Schroeder, T.H. et al. J. Immunol. 166, 7410–7418 (2001).

    Article  CAS  Google Scholar 

  5. Boucher, R.C. Eur. Respir. J. 23, 146–158 (2004).

    Article  CAS  Google Scholar 

  6. Murphy, T.F. & Sethi, S. Drugs Aging 19, 761–775 (2002).

    Article  Google Scholar 

  7. Guilbault, C. et al. Am. J. Respir. Cell Mol. Biol. 38, 47–56 (2008).

    Article  CAS  Google Scholar 

  8. Di, A. et al. Nat. Cell Biol. 8, 933–944 (2006).

    Article  CAS  Google Scholar 

  9. Haggie, P.M. & Verkman, A.S. J. Biol. Chem. 282, 31422–31428 (2007).

    Article  CAS  Google Scholar 

  10. Poschet, J.F. et al. J. Biol. Chem. 277, 13959–13965 (2002).

    Article  CAS  Google Scholar 

  11. Wood, D.M. & Smyth, A.R. Cochrane Database Syst. Rev. CD004197 (2006).

  12. Donaldson, S.H. et al. N. Engl. J. Med. 354, 241–250 (2006).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pier, G. Dropping acid to help cystic fibrosis. Nat Med 14, 367–369 (2008). https://doi.org/10.1038/nm0408-367

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm0408-367

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing