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Immune cells may fend off Alzheimer disease

Nature Medicine volume 13, pages 408–409 (2007)Cite this article

Chemokines in the brain recruit immune cells from the blood or from within the brain. Disrupting this line of communication exacerbates disease in mouse models of Alzheimer disease (pages 432–438).

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Figure 1: Microglia and monocytes may counteract Alzheimer disease through Ccr2-mediated recruitment to Aβ aggregates in the CNS.

Kim Caesar

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Authors and Affiliations

  1. Markus Britschgi and Tony Wyss-Coray are in the Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA.,

    Markus Britschgi & Tony Wyss-Coray

  2. Tony Wyss-Coray is also at the Geriatric Research, Education and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, California 94304, USA. twc@stanford.edu,

    Tony Wyss-Coray

Authors
  1. Markus Britschgi
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  2. Tony Wyss-Coray
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Britschgi, M., Wyss-Coray, T. Immune cells may fend off Alzheimer disease. Nat Med 13, 408–409 (2007). https://doi.org/10.1038/nm0407-408

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