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Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells

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Figure 1: In vitro effects of conditioned medium.
Figure 2: In vivo effects of concentrated conditioned medium from MSCs exposed to hypoxia.

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Acknowledgements

This work was supported in part by US National Institutes of Health Grants HL 72010, HL73219, HL 58516, HL 35610 (to V.J.D.) and HL 5320, HL 63985 (J.S.I). M. Gnecchi was partially supported by a research award from the University of Pavia and IRCCS Policlinico San Matteo, Pavia, Italy.

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Correspondence to Victor J Dzau.

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Gnecchi, M., He, H., Liang, O. et al. Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells. Nat Med 11, 367–368 (2005). https://doi.org/10.1038/nm0405-367

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