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Polygenic or Pollyanna?

A study suggesting that many genes, each conferring a small risk, account for most cases of breast cancer could have important implications for population-based prevention programs—provided that the genes can be identified.

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Figure 1: Different models of the distribution of breast-cancer risk in the population and in breast cancer cases.

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Foulkes, W. Polygenic or Pollyanna?. Nat Med 8, 328–330 (2002). https://doi.org/10.1038/nm0402-328

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