The knockout rat pack

The rat is the preferred model organism in many fields of biomedicine, such as toxicology testing. But when it comes to disease models, rats have been upstaged by mice, which traditionally were far easier to genetically engineer. Elie Dolgin follows the tale of the researchers who are bringing the rat back into the race.

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Dolgin, E. The knockout rat pack. Nat Med 16, 254–257 (2010).

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