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When integrins fail to integrate

Three studies implicate Kindlin-3, a molecule that mediates signaling through integrins, in a rare disorder characterized by spontaneous bleeding and susceptibility to infection (pages 300–305, 306–312 and 313–318).

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Figure 1: The right touch.

Katie Vicari

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Hidalgo, A., Frenette, P. When integrins fail to integrate. Nat Med 15, 249–250 (2009). https://doi.org/10.1038/nm0309-249

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