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Mycobacterium tuberculosis virulence: lipids inside and out

Nature Medicine volume 13, pages 284–285 (2007)Cite this article

During infections, Mycobacterium tuberculosis has to acquire nutrients and resist host defense. Lipids are important for both: host-derived lipids provide food, whereas pathogen-derived lipids mediate immune suppression.

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Figure 1: Anaplerotic reactions needed for growth with sugars or lipids and immunomodulation by phenolic glycolipids (PGL).

Simon Fenwick

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Authors and Affiliations

  1. Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, New York 10021, USA. sae2004@med.cornell.edu or dis2003@med.cornell.edu,

    Sabine Ehrt & Dirk Schnappinger

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  1. Sabine Ehrt
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  2. Dirk Schnappinger
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The authors declare no competing financial interests.

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Ehrt, S., Schnappinger, D. Mycobacterium tuberculosis virulence: lipids inside and out. Nat Med 13, 284–285 (2007). https://doi.org/10.1038/nm0307-284

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