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Defining the 'survivasome' of Mycobacterium tuberculosis

Identification of drug targets in M. tuberculosis is a challenge for bench science. High-throughput mutagenesis with transposons together with microarray-based genome and transcriptome profiling has begun to meet this challenge.

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Figure 1: Transposon site hybridization (TraSH).

Simon Fenwick


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Lamichhane, G., Bishai, W. Defining the 'survivasome' of Mycobacterium tuberculosis. Nat Med 13, 280–282 (2007).

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