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Long-distance affair with adrenal GRK2 hangs up heart failure

Modulation of events regulated by α2-adrenergic receptors counteracts heart failure by restoring proper signaling from the adrenal gland to the heart (pages 315–323).

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Figure 1: Analogy between a G protein–coupled receptor module and a conventional stereo-audio amplifier.

Katie Ris


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Liggett, S. Long-distance affair with adrenal GRK2 hangs up heart failure. Nat Med 13, 246–248 (2007).

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