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The ABCs of β-cell dysfunction in type 2 diabetes

Cholesterol toxicity may damage pancreatic β-cells, leading to decreased insulin secretion and impaired glucose tolerance (pages 340–347).

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Figure 1: Pathways involved in insulin secretion in pancreatic β-cells.

Katie Ris


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Chakravarthy, M., Semenkovich, C. The ABCs of β-cell dysfunction in type 2 diabetes. Nat Med 13, 241–242 (2007).

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