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Nucleus hears axon's pain

Nature Medicine volume 10, pages 236–237 (2004)Cite this article

Upon injury, axons can send a message to the cell body to implement repair programs. This message is now shown to require a complex of the microtubule motor dynein and proteins that mediates nuclear-cytoplasmic transport.

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Figure 1: A model for the retrograde transport of axonal injury signals to the cell soma.

Kimberly Caesar

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Authors and Affiliations

  1. Department of Neurosciences, University of California, San Diego, La Jolla, 92093-0626, California, USA

    Armin Blesch & Mark H Tuszynski

  2. also at the Veterans Affairs Medical Center, La Jolla, 92165, California, USA

    Mark H Tuszynski

Authors
  1. Armin Blesch
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  2. Mark H Tuszynski
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Blesch, A., Tuszynski, M. Nucleus hears axon's pain. Nat Med 10, 236–237 (2004). https://doi.org/10.1038/nm0304-236

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