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siRNAs knock down hepatitis

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The power of small RNAs to shut down specific gene activities has now been brought to bear on an animal model of hepatitis. Mice infused with an siRNA against a cell death receptor recover liver function after experimentally induced injury (pages 347–351).

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Figure 1: RNAi silencing.

Kimberly Homer

Change history

  • 27 March 2003

    This was incorrect in in print. The request to make the change before a print erratum is published was approved by Linda Miller. Replaced Figure 1 as per the note.


  1. NOTE: In the version of this article initially published online and in print, Figure 1 was incorrect. The hydroxyl and phosphate groups were incorrectly placed on the siRNA duplexes. This mistake has been corrected in the HTML version. This correction has been appended to the PDF and print versions.


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Zamore, P., Aronin, N. siRNAs knock down hepatitis. Nat Med 9, 266–267 (2003).

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