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Blocking bacterial enterotoxins

Nature Medicine volume 6, pages 257–258 (2000)Cite this article

Intestinal infections with enteropathogenic Escherichia coli are potentially devastating and difficult to treat. Outbreaks linked to food-borne spread of the bacteria have occurred repeatedly in the US in recent years. New approaches to neutralizing the bacterial toxins responsible for the worst effects of the disease may provide lifesaving tools for clinicians (265–270 ).

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Figure 1: General structure of bacterial enterotoxin, based on E. coli heat-labile toxin as a model.

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Authors and Affiliations

  1. Chiron Corporation, 4560 Horton St., California, 94608, Emeryville, USA

    John J. Donnelly & Rino Rappuoli

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  1. John J. Donnelly
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  2. Rino Rappuoli
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Donnelly, J., Rappuoli, R. Blocking bacterial enterotoxins. Nat Med 6, 257–258 (2000). https://doi.org/10.1038/73095

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