News & Views | Published:

Preemptive therapy for genetic disease

Nature Medicine volume 2, pages 161162 (1996) | Download Citation


In utero stem cell transplantation for inherited blood cell disorders.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1.

    et al. Successful treatment of X-linked recessive severe combined immunodeficiency (X-SCID) by the in utero transplantation of CD34 enriched paternal bone marrow cells. Blood 86, 125a (1995).

  2. 2.

    et al. Development of immunity in human severe primary T cell deficiency following haploidentical bone marrow stem cell transplantation. J. Immunoi. 136, 2398–2407 (1986).

  3. 3.

    et al. Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans. Cell 73, 147–157 (1993).

  4. 4.

    and In utero hematopoietic stem cell transplants for inherited diseases. Am. J. Pediat. Hematol. J. Oncol. 16, 35–42 (1994).

  5. 5.

    et al. Mixed chimerism in thalassemic patients after bone marrow transplantation. B.M.T. 10, 143–146 (1992).

  6. 6.

    et al. Analysis of β-globin mutations shows stable mixed chimerism in patients with thalassemia after bone marrow transplantation. Blood 86, 3241–3246 (1995).

  7. 7.

    et al. Marrow transplantation in patients with thalassemia responsive to chelation therapy N. Engl. J. Med. 329, 840–844 (1993).

Download references

Author information


  1. Divisions of Hematology and Medical Genetics University of Washington Seattle, Washington, 98195, USA

    • C.Anthony Blau
    •  & George Stamatoyannopoulos


  1. Search for C.Anthony Blau in:

  2. Search for George Stamatoyannopoulos in:

About this article

Publication history



Further reading

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing