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Stemming a tumor with a little miR

Nature Medicine volume 17, pages 162164 (2011) | Download Citation

A microRNA decreases the expression of the adhesion molecule CD44 in prostate cancer stem cells (CSCs), blocking tumor growth and metastasis in mice (pages 211–215). Systemic delivery of this negative regulator may open new avenues for targeting CSCs to halt cancer.

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Author information

Affiliations

  1. Max S. Wicha is at the University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, USA.

    • Max S Wicha

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Competing interests

M.S.W. is a scientific advisor and holds equity in Oncomed Pharmaceuticals.

Corresponding author

Correspondence to Max S Wicha.

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DOI

https://doi.org/10.1038/nm0211-162

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