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Sugar rush bleeds the brain

Nature Medicine volume 17, pages 161162 (2011) | Download Citation

Hyperglycemia is a risk factor for poor outcomes after intracerebral hemorrhage (ICH), but what drives its effects on ICH is unknown. A new study shows that plasma kallikrein mediates hyperglycemia-induced hematoma expansion in rats and mice with ICH by inhibiting blood platelets (pages 206–210).

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Author information

Affiliations

  1. Bernhard Nieswandt is in the Department of Vascular Medicine, University Hospital, University of Würzburg, Würzburg, Germany and at the Rudolf Virchow Center, the Deutsche Forschungsgemeinschaft Research Center for Experimental Biomedicine, University of Würzburg, Würzburg, Germany.

    • Bernhard Nieswandt
  2. Guido Stoll is in the Department of Neurology, University of Würzburg, Würzburg, Germany.

    • Guido Stoll

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Bernhard Nieswandt.

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DOI

https://doi.org/10.1038/nm0211-161

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