Hyperglycemia is a risk factor for poor outcomes after intracerebral hemorrhage (ICH), but what drives its effects on ICH is unknown. A new study shows that plasma kallikrein mediates hyperglycemia-induced hematoma expansion in rats and mice with ICH by inhibiting blood platelets (pages 206–210).
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Nieswandt, B., Stoll, G. Sugar rush bleeds the brain. Nat Med 17, 161–162 (2011). https://doi.org/10.1038/nm0211-161
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DOI: https://doi.org/10.1038/nm0211-161