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Globular warming: how fat gets to the furnace

Nature Medicine volume 17, pages 157159 (2011) | Download Citation

Triglyceride-rich lipoproteins (TRLs) transport lipid calories to tissues that need energy, but TRLs can also contribute to obesity and vascular disease. A newly discovered pathway shows how cold exposure increases the uptake and combustion of TRLs by brown adipose tissue, thereby correcting harmful hyperlipidemias (pages 200–205).

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Affiliations

  1. Kevin Jon Williams is in the Section of Endocrinology, Diabetes and Metabolism, the Department of Medicine and the Cardiovascular Research Center, Department of Physiology, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

    • Kevin Jon Williams
  2. Edward A. Fisher is in the Leon H. Charney Division of Cardiology and the Marc and Ruti Bell Program in Vascular Biology and Disease, New York University School of Medicine, New York, New York, USA. He is also in the Department of Cardiovascular Medicine, University of Oxford, Oxford, UK.

    • Edward A Fisher

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Competing interests

The authors declare no competing financial interests.

Corresponding authors

Correspondence to Kevin Jon Williams or Edward A Fisher.

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DOI

https://doi.org/10.1038/nm0211-157

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