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Globular warming: how fat gets to the furnace

Nature Medicine volume 17, pages 157–159 (2011)Cite this article

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Triglyceride-rich lipoproteins (TRLs) transport lipid calories to tissues that need energy, but TRLs can also contribute to obesity and vascular disease. A newly discovered pathway shows how cold exposure increases the uptake and combustion of TRLs by brown adipose tissue, thereby correcting harmful hyperlipidemias (pages 200–205).

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Figure 1: Pathways for catabolism of triglyceride-rich lipoproteins.

Katie Vicari

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Authors and Affiliations

  1. the Department of Medicine and the Cardiovascular Research Center, Department of Physiology, Kevin Jon Williams is in the Section of Endocrinology, Diabetes and Metabolism, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.,

    Kevin Jon Williams

  2. Edward A. Fisher is in the Leon H. Charney Division of Cardiology and the Marc and Ruti Bell Program in Vascular Biology and Disease, USA. He is also in the Department of Cardiovascular Medicine, New York University School of Medicine, New York, New York, University of Oxford, Oxford, UK.,

    Edward A Fisher

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  1. Kevin Jon Williams
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  2. Edward A Fisher
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Correspondence to Kevin Jon Williams or Edward A Fisher.

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Williams, K., Fisher, E. Globular warming: how fat gets to the furnace. Nat Med 17, 157–159 (2011). https://doi.org/10.1038/nm0211-157

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