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Inflammatory proteinase slips into tumor cells

Inflammatory cells can promote tumor cell proliferation, but the range of mechanisms has not been fully explored. A proteinase produced by neutrophils is now shown to enter tumor cells and promote their proliferation (pages 219–223).

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Figure 1: Neutrophil elastase controls tumor cell proliferation.

Katie Vicari

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Correspondence to Barbara Fingleton.

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Fingleton, B. Inflammatory proteinase slips into tumor cells. Nat Med 16, 161–163 (2010). https://doi.org/10.1038/nm0210-161

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