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Safer, longer-lasting regulatory T cells with β-catenin

Expressing a stabilized form of β-catenin extends the lifespan of regulatory T cells— one goal of therapies that take advantage of these cells (pages 162–169).

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Figure 1: Potential role of Wnt signaling in Treg survival.

Katie Ris-Vicari

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Bluestone, J., Hebrok, M. Safer, longer-lasting regulatory T cells with β-catenin. Nat Med 14, 118–119 (2008). https://doi.org/10.1038/nm0208-118

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