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Stressed and depressed

Knocking out a stress hormone receptor in the forebrain of mice generates symptoms of depression, which are alleviated by the antidepressant imipramine. The findings begin to unravel the intricate relationship between stress and depression.

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Figure 1: Stress and depression.

Ann Thomson


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Akil, H. Stressed and depressed. Nat Med 11, 116–118 (2005).

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