Presenilins, amyloid-β and Alzheimer's disease

Evidence is accumulating that presenilin gene mutations may contribute to the pathogenesis of Alzheimer's disease by increasing amyloid β-protein production (pages 67–72).

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Lamb, B. Presenilins, amyloid-β and Alzheimer's disease. Nat Med 3, 28–29 (1997).

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