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Treating trisomies: Prenatal Down's syndrome therapies explored in mice

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  1. Larsen, K.B. Ann. Anat. 109, 421–427 (2008).

    Article  Google Scholar 

  2. Bahado-Singh, R.O. et al. Am. J. Obstet. Gynecol. 167, 1009–14 (1992).

    Article  CAS  Google Scholar 

  3. Reeves, R.H. et al. Nat. Genet. 11, 177–184 (1995).

    Article  CAS  Google Scholar 

  4. Gardiner, K.J. Drug Des. Devel. Ther. 9, 103–125 (2015).

    CAS  PubMed  Google Scholar 

  5. Belichenko, P.V. et al. Comp. Neurol. 480, 281–298 (2004).

    Article  Google Scholar 

  6. Bartesaghi, R. et al. J. Neurosci. 35, 13843–13852 (2015).

    Article  Google Scholar 

  7. Guidi, S. et al. Brain 137, 380–401 (2014).

    Article  Google Scholar 

  8. Malberg, J.E., Eisch, A.J., Nestler, E.J. & Duman, R.S. J. Neurosci. 20, 9104–9110 (2000).

    Article  CAS  Google Scholar 

  9. Reefhuis, J., Devine, O., Friedman, J.M., Louik, C. & Honein, M.A. B.M.J. 351, h3190 (2015).

    Article  Google Scholar 

  10. Bianchi, D. Nat. Med. 18, 1041–1051 (2012).

    Article  CAS  Google Scholar 

  11. Moon, J. et al. Behav. Neurosci. 124, 346–361 (2010).

    Article  CAS  Google Scholar 

  12. De La Torre, R. et al. Mol. Nutr. Food Res. 58, 278–288 (2014).

    Article  Google Scholar 

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Kuehn, B. Treating trisomies: Prenatal Down's syndrome therapies explored in mice. Nat Med 22, 6–7 (2016).

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