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Vessel remodeling in the newborn: platelets fill the gap

Nature Medicine volume 16, pages 33–35 (2010)Cite this article

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In newborn infants, permanent closure of a major blood vessel connecting the main pulmonary artery to the aorta is essential to allow adequate circulation of blood to major organs. Platelet aggregation now emerges as a crucial step in this process in newborn mice and, possibly, in preterm infants (pages 75–82).

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Figure 1: Schematic of the ductus arteriosus in the full-term human fetus and newborn (left) and in the full-term mouse fetus and newborn (right).

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Authors and Affiliations

  1. Ronald Clyman is in the Cardiovascular Research Institute and Department of Pediatrics, University of California San Francisco, San Francisco, California, USA.,

    Ronald Clyman

  2. Sylvain Chemtob is in the Departments of Pediatrics, Ophthalmology and Pharmacology, Centre Hospitalier Universitaire Ste. Justine, Montreal, Canada.,

    Sylvain Chemtob

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  1. Ronald Clyman
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  2. Sylvain Chemtob
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Correspondence to Sylvain Chemtob.

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Clyman, R., Chemtob, S. Vessel remodeling in the newborn: platelets fill the gap. Nat Med 16, 33–35 (2010). https://doi.org/10.1038/nm0110-33

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