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Mesenchymal stem cells combat sepsis

A new approach to the treatment of sepsis relies on the infusion of mesenchymal stem cells, multipotent cells used experimentally to treat a range of medical conditions. In mouse models, the cells seem to reprogram immune cells that can contribute to sepsis (pages 42–49).

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Figure 1: Bone marrow–derived mesenchymal stem cells (BMSCs) reprogram macrophages and counteract sepsis.


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Tyndall, A., Pistoia, V. Mesenchymal stem cells combat sepsis. Nat Med 15, 18–20 (2009).

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