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Hope in sight for retinoblastoma

The retinoblastoma gene (RB) was the first tumor suppressor gene cloned. But, until recently, little clinical progress had been made to target human tumors deficient in RB function. A new approach emerges from studying retinoblastoma tumors.

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Figure 1: Possible points of therapeutic interventions against human cancers with alterations in the RB pathway.

Katie Ris


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Sage, J. Hope in sight for retinoblastoma. Nat Med 13, 30–31 (2007).

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