Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

IL-23: a master regulator in Crohn disease

Three studies should shift thinking about the causes of inflammatory bowel disease. It seems that researchers have been focusing on the wrong cytokine as a driving force.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: Shifting paradigms in the pathogenesis of IBD.

Katie Ris

References

  1. Duerr R.H. et al. Science 314, 1461–1463 (2006).

    CAS  Article  Google Scholar 

  2. Hue, S. et al. J. Exp. Med. 203, 2473–2483 (2006).

    CAS  Article  Google Scholar 

  3. Kullberg, M.C. et al. J. Exp. Med. 203, 2485–2494 (2006).

    CAS  Article  Google Scholar 

  4. Oppmann, B. et al. Immunity 13, 715–725 (2000).

    CAS  Article  Google Scholar 

  5. Becker, C. et al. J. Clin. Invest. 112, 693–706 (2003).

    CAS  Article  Google Scholar 

  6. Neurath, M.F., Fuss, I., Kelsall, B.L., Stuber, E. & Strober, W. J. Exp. Med. 182, 1281–1290 (1995).

    CAS  Article  Google Scholar 

  7. Simpson, S.J. et al. J. Exp. Med. 187, 1225–1234 (1998).

    CAS  Article  Google Scholar 

  8. Ivanov, I.I. et al. Cell 126, 1121–1133 (2006).

    CAS  Article  Google Scholar 

  9. Uhlig, H.H. et al. Immunity 25, 309–318 (2006).

    CAS  Article  Google Scholar 

  10. Yen, D. et al. J. Clin. Invest. 116, 1310–1316 (2006).

    CAS  Article  Google Scholar 

  11. Mannon, P.J. et al. N. Engl. J. Med. 351, 2069–2079 (2004).

    CAS  Article  Google Scholar 

  12. Becker, C. et al. J. Immunol. 177, 2760–2764 (2006).

    CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Neurath, M. IL-23: a master regulator in Crohn disease. Nat Med 13, 26–27 (2007). https://doi.org/10.1038/nm0107-26

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm0107-26

Further reading

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing