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Is leptin an important physiological regulator of CRP?

Nature Medicine volume 13, pages 19–21 (2007)Cite this article

Chen et al. reply:

To begin with, Gertler's group used several different methods to evaluate the interaction between human leptin and human CRP. Due to the fact that only one of the experimental systems they used was similar to what we have described in our published study1, we cannot be entirely sure about the discrepancies between the observations of our groups. However, several of the experimental designs and conditions used by Gertler et al. are unfavorable to the study of the effects of human CRP on the actions of leptin and may thus account for the discrepancies.

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  1. Department of Cell Biology and Physiology, University of Pittsburgh, 3500 Terrace Street S-326, Pittsburgh, 15261, Pennsylvania, USA

    Allan Zhao

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Zhao, A. Is leptin an important physiological regulator of CRP?. Nat Med 13, 19–21 (2007). https://doi.org/10.1038/nm0107-19

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