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The tangled path to glucose production

Liver glucose production is crucial to survival during fast and is abnormally elevated in diabetes. Studies of the transcriptional coactivator Torc2 redefine the mechanism by which cAMP signaling affects fasting-induced glucogenesis.

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Figure 1: Pathways of gluconeogenesis.

Simon Fenwick

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Matsumoto, M., Accili, D. The tangled path to glucose production. Nat Med 12, 33–34 (2006). https://doi.org/10.1038/nm0106-33

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