Mutations in the clock gene Per2 influence alcohol consumption, as revealed by studies in mice and humans. In mice, this effect seems to be mediated by an excess of glutamate in the brain (pages 35–42).
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Yuferov, V., Bart, G. & Kreek, M. Clock reset for alcoholism. Nat Med 11, 23–24 (2005). https://doi.org/10.1038/nm0105-23
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DOI: https://doi.org/10.1038/nm0105-23
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