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Bacteria spurned by self-absorbed cells

Three studies show that cells are protected against intracellular pathogens by autophagy, a process that degrades cytoplasmic components in bulk. The work may have implications for the development of vaccines against pathogens such as Mycobacterium tuberculosis, Streptococcus pyogenes and Shigella flexneri.

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Figure 1: Electron micrograph showing Mycobacterium avium in a late autophagosome.

Courtesy of Chantal de Chastellier

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Gorvel, JP., de Chastellier, C. Bacteria spurned by self-absorbed cells. Nat Med 11, 18–19 (2005). https://doi.org/10.1038/nm0105-18

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