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In vivo imaging reveals estrogen receptor's hidden personality

Post-menopausal women are treated with estrogen-receptor binding compounds during hormone replacement therapy. But new imaging studies in mice hint that the estrogen receptor may be responding primarily to estrogen-independent stimuli in some tissues (pages 82–86).

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Figure 1: Mouse model for hormone-dependent and -independent regulation of estrogen receptors (ERs), as revealed by in vivo bioluminescent imaging.

Kimberly Homer

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Greene, G. In vivo imaging reveals estrogen receptor's hidden personality. Nat Med 9, 22–23 (2003). https://doi.org/10.1038/nm0103-22

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