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Lipid metabolic reprogramming in hepatic ischemia–reperfusion injury

Nature Medicine volume 24, pages 67 (2018) | Download Citation

In a recent study of hepatic ischemia–reperfusion injury (IRI), Zhang et al. use tandem 'omics' approaches in mice, pigs, and nonhuman primates to identify lipid metabolic reprogramming as a key determinant of IRI, thus providing novel mechanistic and therapeutic insights.

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Author information

Affiliations

  1. Satdarshan P. Monga is at the Division of Experimental Pathology, Department of Pathology; the Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine; and the Pittsburgh Liver Research Center, University of Pittsburgh Medical Center and University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

    • Satdarshan P Monga

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Competing interests

The author declares no competing financial interests.

Corresponding author

Correspondence to Satdarshan P Monga.

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DOI

https://doi.org/10.1038/nm.4468

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