In a recent study of hepatic ischemia–reperfusion injury (IRI), Zhang et al. use tandem 'omics' approaches in mice, pigs, and nonhuman primates to identify lipid metabolic reprogramming as a key determinant of IRI, thus providing novel mechanistic and therapeutic insights.
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Monga, S. Lipid metabolic reprogramming in hepatic ischemia–reperfusion injury. Nat Med 24, 6–7 (2018). https://doi.org/10.1038/nm.4468
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DOI: https://doi.org/10.1038/nm.4468
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